教育经历
2004-09至2009-07，中国科学院生物物理研究所，脑与认知科学国家重点实验室，博士 1997-09至2001-07，湖北师范大学，物理系，学士
From 2004-09 to 2009-07，Institute of Biophysics of the Chinese Academy of Sciences, State key laboratory of brain and cognitive sciences, Doctor From 1997-09 to 2001-07，Hubei Normal University, College of physical education，Bacholar
工作经历
(1) 2014-12至现在，北京脑重大疾病研究院，低氧适应医学研究平台，技师 (2) 2012-07至2014-11，中国科学院生物物理研究所，生物大分子国家重点实验室，博士后， (3) 2009-08至2012-06，临沂大学，生命科学学院，讲师 (4) 2001-09至2004-07，湖北省沙市中学，高中教师
(1) From 2014-12 to now, Beijing Institute for Brain Disorders, Hypoxic adaptive medicine research platform, Technician (2) From 2012-07 to 2014-11, Institute of Biophysics of the Chinese Academy of Sciences, National laboratory of biomacromolecules, Postdoctor (3) From 2009-08 to 2012-06, Linyi University, College of Life Sciences, lecturer (4) From 2001-09 to 2004-07, Hubei Shashi Middle School, High school teacher
研究概述
本人一直致力于用电生理、生化等方法研究帕金森病、阿尔茨海默病等神经退行性疾病的发病及治疗机制，以及神经免疫系统淋巴细胞分化与功能异常的机制研究。证明了黑质多巴胺能神经元上的BKCa离子通道的存在；乙醇脱氢酶5对神经元分化以及衰老引起的学习与记忆能力退化的影响及机制；并揭示了电针能通过调节皮层-纹状体通路的突触可塑性来改善帕金森病运动能力异常的作用机制。
We have been committed to using electrophysiological, biochemical and other methods to study the pathogenesis and treatment mechanism of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, as well as the mechanism of lymphocyte differentiation and dysfunction of nervous immune system. The existence of BKCa ion channel on dopaminergic neurons in substantia nigra was proved; The effect and mechanism of alcohol dehydrogenase 5 on neuronal differentiation and degradation of learning and memory induced by aging; We also reveal the mechanism that electroacupuncture improve the abnormal motor ability of Parkinson's disease by regulating the synaptic plasticity of cortical striatal pathway.
代表成果
发表文章 （1）Su W, Song X, Ji JJ (2010) Functional expression of a large-conductance Ca2+-activated K+ channel in mouse substantia nigra pars compacta dopaminergic neurons. Neuroscience letters 471:1-5. （2）Wu K*, Ren R*, Su W*, Wen B, Zhang Y, Yi F, Qiao X, Yuan T, Wang J, Liu L, Izpisua Belmonte JC, Liu GH, Chen C (2014) A novel suppressive effect of alcohol dehydrogenase 5 in neuronal differentiation. The Journal of biological chemistry 289:20193-20199. （3）He Y, Fang Y, Zhai B, Liu X, Zhu G, Zhou S, Xu Y, Wang X, Su W#, Wang R# (2021) Gm40600 promotes CD4(+) T-cell responses by interacting with Ahnak. Immunology 164:190-206. （4）李华, 朱改只, 周珊, 徐雅琪, 崔秀玉, 周岩, 王仁喜#, 粟文婷# (2021) 老年小鼠海马离体脑片长时程增强方法的建立. 实验技术与管理 38:51-54, 60.
